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| 血清H2S水平与骨密度的相关性初步研究 |
| Preliminary study of the correlation between serum H2S and bone mineral density |
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| DOI：10.3969/j.issn.1006-7108.2019.02.009 |
| 中文关键词: 骨质疏松 硫化氢 骨密度 髋部骨折 |
| 英文关键词:osteoporosis hydrogen sulfide bone mineral density hip fracture |
| 基金项目:苏州市科技指导项目（sysd2016031）；昆山市社会发展科技专项（ks1531） |
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| 中文摘要: |
| 目的 血清H2S水平与骨质疏松的相关性。方法 收集2015年10月至2017年10月112例在江苏昆山地区体检和门诊就诊人员的资料，其中男82例，女30例，年龄25～86岁，平均(51．40±10.60)岁；采用DEXA骨密度仪检测该人群的骨密度，以及采用亚甲基蓝法测定血清H2S水平。结果 体内血清H2S水平与髋部骨密度呈正相关，与腰椎骨密度无明显相关性。结论 血清H2S水平与髋部骨密度存在相关，可能是髋部骨密度下降的独立危险因素，H2S可能是骨密度的保护因素。 |
| 英文摘要: |
| Objective To study the correlation between serum H2S and osteoporosis. Methods From October 2015 to October 2017, 112 cases were collected from individuals attended physical examination or clinics in Jiangsu Kunshan area, 82 cases were male, 30 were female, age ranged 25-86 years, with an average of 51.40±10.60 years. Bone mineral density (BMD) was measured by dual-energy x-ray absorptiometry (DEXA), and the methylene blue method was used for the determination of serum H2S levels. Results Serum H2S levels positively correlated with BMD at the hip, but had no significant correlation with BMD at the spine. Conclusion Serum H2S level is associated with hip bone mineral density, thus could be an independent risk factor for the decrease of bone density in the hip, and H2S may also be a protective factor for bone density. |
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