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| 老年女性血清25-羟基维生素D的独立相关因素 |
| Independent factors associated with serum 25-hydroxyvitamin D in elder women |
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| DOI：10.3969/j.issn.1006-7108.2019.05.015 |
| 中文关键词: 25-羟基维生素D 甲状旁腺素 晒太阳 老年人 女性 |
| 英文关键词:25-hydroxyvitamin D parathyroid hormone basking aged woman |
| 基金项目:浙江省医药卫生科技计划项目（2016ZDA002，2018KY222） |
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| 中文摘要: |
| 目的 通过筛选老年女性血清25-羟基维生素D[25(OH)D]的独立相关因素，寻找提高老年女性血清25(OH)D的方法。方法 对280例老年女性进行伴随疾病和生活方式的调查，并进行骨代谢、血液生化、性激素和贫血等指标的检测，运用多元回归分析方法筛选老年女性血清25(OH)D的独立相关因素。结果 老年女性血清25(OH)D的独立相关因素包括血PTH(β=-0.097，P＜0.01)、血磷(β=-18.144，P＜0.01)、血钙(β=19.912，P＜0.01)、服用复方钙剂(β=5.362，P＜0.01)和晒太阳(β=0.974，P＜0.05)。结论 坚持晒太阳、服用复方钙剂和补充维生素D，可能是提高老年女性血清25(OH)D水平的重要方法。 |
| 英文摘要: |
| Objective To probe into the ways to improve serum 25-hydroxyvitamin D(25OHD) by means of screening independent factors associated with serum 25OHD in elder women. Methods A cross-sectional survey was conducted in a cohort comprising 280 women. All subjects underwent a survey on underlying chronic diseases and lifestyle factors. The serum levels of bone metabolism markers, biomedical index, anemia-related, index as well as sex steroids were detected. Univariate analysis and multivariate regression analysis were performed to discover independent factors associated with 25OHD. Results It was showed that serum parathyroid hormone (β=-0.097, P<0.01), potassium (β=-18.144, P<0.01), calcium (β=19.912, P<0.01), calcium compound supplement (β=5.362, P<0.01), and sun exposure (β=0.974, P<0.05) were independent 25OHD-associated factors. Conclusion Sun exposure and vitamin D and calcium supplement may help increase serum 25OHD in elder women. |
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