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| 基于中医时间医学探讨绝经后骨质疏松症发生与发展 |
| Exploration of the occurrence and development of postmenopausal osteoporosis based on time medicine theory of traditional Chinese medicine |
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| DOI：10.3969/j.issn.1006-7108.2026.05.018 |
| 中文关键词: 绝经后骨质疏松症 中医时间医学 生物钟 |
| 英文关键词:postmenopausal osteoporosis Chinese time medicine biological clock |
| 基金项目:浙江省自然科学基金重点项目（LZ22H270002)；浙江省“尖兵领雁+X”科技计划（2025C02193） |
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| 中文摘要: |
| 昼夜节律紊乱与代谢性疾病的关联极为紧密，其可影响绝经后骨质疏松症（postmenopausal osteoporosis, PMOP）的发生与发展。中医时间医学中，阴阳平衡、营卫气血的流转以及四季更替的规律与现代生物节律的概念在本质上具有诸多相似之处。立足于中医时间医学的理论基础，可以认为PMOP的发病与肾气-天癸的节律变化、营卫气血的运行规律以及四季节律的异常之间存在着紧密的联系。通过对PMOP发病及发展过程中相关时间节律的深入分析，能够进一步深化从中医时间医学视角对PMOP发病机制的理解，从而为临床治疗该病症提供全新的思路与方法。 |
| 英文摘要: |
| Circadian rhythm disorders are strongly associated with metabolic diseases, which may affect the development of postmenopausal osteoporosis (PMOP). In traditional Chinese medicine (TCM), the balance of yin and yang, the flow of qi and blood, and the change of seasons have many similarities with the modern concept of biological rhythms. Based on the theoretical foundation of TCM time medicine, it can be assumed that there is a close connection between the onset of PMOP and the rhythmic changes of kidney qi - Tian Gui, the flow of Ying Wei and qi blood, and the abnormalities of the four seasons' rhythms. The in-depth analysis of the related time rhythms in the onset and development of PMOP may further deepen the understanding of the pathogenesis of PMOP from the perspective of TCM time medicine, and thus provide brand-new ideas and methods for the clinical treatment of this disease. |
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