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| 不同减重方式对老年肥胖患者骨量流失影响研究进展 |
| Effects of weight loss strategies on bone mineral density decline in elderly patients with obesity: An updated review |
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| DOI：10.3969/j.issn.1006-7108.2026.08.018 |
| 中文关键词: 老年人 肥胖 减重 骨质疏松 骨密度 |
| 英文关键词:older adults obesity weight management osteoporosis bone mineral density |
| 基金项目:四川省科技计划项目(2017SZ0148)；国家卫生健康委核技术医学转化重点实验室开放课题资助项目(2021HYX024)；绵阳市中心医院孵化课题(2022FH013)；绵阳市中心医院IIT项目(2025KY-LW037) |
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| 中文摘要: |
| 老年人肥胖是日益严重的公共卫生问题，减重可以预防和改善肥胖相关疾病。然而，越来越多的研究表明减重可引起骨量流失，尤其对老年人骨骼分解代谢效应影响最大，甚至增加骨质疏松和病理性骨折风险。目前减重方式多样，对骨代谢影响也存在差异。为此，本文总结了不同减重方式对老年人骨量流失影响以及相关防治措施的研究进展，为老年人减重方式的选择和骨量流失的防治提供参考。 |
| 英文摘要: |
| Obesity in the elderly represents a growing public health concern. While weight loss may prevent and ameliorate obesity-related commodities, accumulating evidence indicates that it may simultaneously accelerate bone mineral density decline, particularly exacerbating skeletal catabolism in older adults and potentially increasing risks of osteoporosis and pathological fractures. Current weight loss strategies vary considerably in their impacts in bone metabolism. We summarizes recent advances in the understanding of the effects of different weight loss strategies on bone mineral density decline in the aging population and discuss corresponding bone-protective interventions, thereby providing evidence-based guidance for optimizing weight management while preserving skeletal health in elderly individuals. |
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